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legal lean syrup  is a medication used to treat coughing and cold symptoms. It is a combination of an antihistamine and a decongestant. Codeine is an opioid pain medication. It is also a cough suppressant.

Common side effects of legal lean syrup include: Drowsiness, Dizziness, Nausea, Vomiting

Dosage and Administration of Actavis Promethazine Codeine

The recommended dose of legal lean syrup for most people is one or two teaspoons (10-20 mL) every four to six hours as needed. The maximum recommended dose is four teaspoons (40 mL) in a 24-hour period. You should not take more than the recommended dose without first talking to your doctor.

If you are taking thc lean syrup for the first time, it is important to start with a lower dose and increase it gradually as needed. This will help minimize the risk of side effects.

When taking legal lean syrup, be sure to follow the directions on the label carefully. Do not take more or less than the recommended dose. Do not take it more often than prescribed.

Actavis Promethazine Codeine

Actavis Promethazine Codeine refers to a promethazine hydrochloride and codeine phosphate oral solution.

The medication combines promethazine, a phenothiazine antihistamine, with codeine, an opioid. FDA-approved promethazine HCl and codeine phosphate oral solution is indicated for temporary relief of cough and upper-respiratory symptoms associated with allergy or the common cold in adults 18 years of age and older.

Product Details

Product Name: Actavis Promethazine Codeine

Active Ingredients: Promethazine hydrochloride and codeine phosphate

Dosage Form: Oral solution

Drug Class: Antihistamine / opioid combination

Prescription Status: Prescription medication

Route: Oral

Current U.S. labeling identifies promethazine HCl and codeine phosphate oral solution as a Schedule V controlled substance.

Active Ingredients

Promethazine Hydrochloride

Promethazine is a phenothiazine derivative with antihistamine properties. It is included in the combination formulation alongside codeine.

Codeine Phosphate

Codeine is an opioid that can suppress coughing and also carries risks associated with opioid medicines, including dependence, misuse, abuse, overdose, and respiratory depression.

Product Form

Promethazine Codeine is supplied as an oral liquid solution.

Current FDA labeling for an approved promethazine HCl and codeine phosphate oral solution identifies the formulation as containing 6.25 mg promethazine hydrochloride and 10 mg codeine phosphate per 5 mL. Product formulations can vary by manufacturer and authorization, so the specific package label should always be checked.

General Medical Use

FDA-approved promethazine HCl and codeine phosphate oral solution is indicated for temporary relief of cough and upper-respiratory symptoms associated with allergy or the common cold in adults 18 years of age and older.

Because codeine is an opioid, the FDA labeling states that it should be reserved for appropriate adult patients after considering the benefits and risks.

Important Safety Information

Promethazine Codeine carries significant safety warnings.

The FDA boxed warning includes risks of:

• Addiction
• Abuse
• Misuse
• Life-threatening respiratory depression
• Accidental ingestion
• Dangerous interactions with other medicines
• Neonatal opioid withdrawal syndrome

Serious or fatal respiratory depression can occur with this medication.

Children and Adolescents

Current FDA labeling states that promethazine HCl and codeine phosphate oral solution is not indicated for patients younger than 18 years of age.

The labeling also identifies serious respiratory-depression risks in pediatric patients and contraindications involving children.

Drug Interactions

Combining promethazine with codeine and other central nervous system depressants can increase the risk of severe sedation and respiratory depression.

The FDA specifically warns about concomitant use with benzodiazepines and other CNS depressants. Alcohol and other substances that depress the central nervous system can also increase risk.

Important Product Note

The exact formulation, manufacturer, packaging, concentration, and labeling should be verified against the original product packaging and current prescribing information.

Do not rely on product photographs, online descriptions, or packaging alone to establish authenticity or composition.

Frequently Asked Questions

What is Actavis Promethazine Codeine?

It refers to a promethazine hydrochloride and codeine phosphate oral-solution formulation.

What are the active ingredients?

The combination contains promethazine hydrochloride and codeine phosphate.

What form does Promethazine Codeine come in?

The medication is available as an oral solution.

What is Promethazine Codeine used for?

FDA-approved promethazine HCl and codeine phosphate oral solution is indicated for temporary relief of cough and upper-respiratory symptoms associated with allergy or the common cold in adults 18 years and older.

Is Promethazine Codeine a prescription medication?

Yes. Current U.S. labeling identifies the product as a prescription medication and a Schedule V controlled substance.

Does Promethazine Codeine contain an opioid?

Yes. Codeine is an opioid component of the medication.

What are the major risks?

Important risks include addiction, abuse, misuse, respiratory depression, accidental ingestion, and dangerous interactions with CNS depressants.

Can children take Promethazine Codeine?

Current FDA labeling does not indicate promethazine HCl and codeine phosphate oral solution for patients younger than 18 years and contains specific pediatric contraindications and warnings.

Official References

FDA — Promethazine HCl and Codeine Phosphate Oral Solution Prescribing Information

DailyMed — Promethazine HCl and Codeine Phosphate Oral Solution

Use the current package labeling and prescribing information for the specific manufacturer and formulation.